Serum C-peptide concentration and prostate cancer
نویسندگان
چکیده
منابع مشابه
ociation between C-Peptide Concentration and Prostate
r Prev Res betes, characterized by perturbations in insulin production and signaling, is inversely associated rostate cancer risk irrespective of stage. Obesity, a diabetes risk factor, is inversely associated with ed disease but positively associated with advanced disease. To understand the complex associaetween hyperinsulinemia and prostate cancer, we evaluated the association of plasma C-pep...
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OBJECTIVE To test the hypothesis that elevated midpregnancy serum insulin (IRI) and C-peptide (CP) concentrations are associated with later development of pregnancy-induced hypertension (PIH), independent of prepregnancy obesity and midpregnancy blood pressure. RESEARCH DESIGN AND METHODS In this prospective study, a cohort of normotensive women, ages > or = years performed a 50-g glucose cha...
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Hyperinsulinemia and obesity-related metabolic disturbances are common and have been associated with increased cancer risk and poor prognosis. To investigate this issue in relation to prostate cancer, we conducted a nested case-control study within the Prostate Cancer Prevention Trial (PCPT), a randomized, placebo-controlled trial testing finasteride versus placebo for primary prevention of pro...
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Background: Prostate specific antigen (PSA) has been used as a screening test for the early detection of prostate cancer (PC) for many years. Although the introduction of PSA test led to a considerable increase in reported prostate cancer cases, there is still some controversy over the sensitivity and specificity of this marker in distinguishing PC patients from those with benign prostate hyper...
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BACKGROUND Lycopene has been promoted for prostate cancer prevention, despite the inconsistency of scientific evidence. METHODS This nested case-control study examined whether serum lycopene was associated with prostate cancer risk among participants in the Prostate Cancer Prevention Trial, a placebo-controlled trial of finasteride for prostate cancer prevention. Presence or absence of cancer...
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ژورنال
عنوان ژورنال: Medicine
سال: 2018
ISSN: 0025-7974
DOI: 10.1097/md.0000000000011771